Hereditary Spastic Paraplegia Stem Cell Treatment Consists of the Following:
200 Million Stem Cell IV
NAD+ and High Dose Vitamin C IV drip after the stem cells
50 Million Stem Cells Administered via Intrathecal Injection
Full Blood Panel
PRICE: $11,000 USD
- Day 1: Arrive and Rest
- Day 2: Bloodwork, Payment and take MSCs out of cultivation
- Day 3: IV, Direct Injections and Intrathecal Treatment
- Day 4: Rest
- Day 5: Fly Home
The intrathecal treatment cannot be done if the patient is on blood thinners. Call for guidance if the patient is taking a blood thinner for alternative recommendations.
Rediscover Mobility with Stem Cell Treatment for Hereditary Spastic Paraplegia at Dream Body Clinic
Are you or a loved one struggling with the debilitating effects of Hereditary Spastic Paraplegia (HSP)?
Transform Your Life with Advanced Stem Cell Therapy at Dream Body Clinic. We understand the challenges and limitations imposed by HSP. Our cutting-edge Mesenchymal Stem Cell (MSC) therapy offers hope and a path to improved mobility and quality of life. Here’s why our treatment stands out:
Expertise and Innovation: Our team of experienced medical professionals specializes in stem cell therapy, employing the latest techniques and research to provide you with the best possible care.
Customized Treatment Plans: We understand that each patient is unique. Our personalized treatment plans are tailored to your specific needs, ensuring the most effective and targeted approach to managing your HSP symptoms. The listed protocol is the most common protocol, but we will do a free consultation and then decide on the proper dosing.
State-of-the-Art Facilities: Dream Body Clinic boasts modern, fully-equipped facilities designed for comfort and care. Our advanced medical technology ensures that you receive the highest standard of treatment in a safe and welcoming environment.
Holistic Approach: Beyond stem cell therapy, we offer a comprehensive approach to health and wellness. Our team provides guidance on lifestyle changes, physical therapy, and nutritional support to maximize the benefits of your treatment.
Benefits of Our Stem Cell Therapy
- Neuroprotection and Regeneration: MSCs have the potential to protect and regenerate damaged neurons, offering a chance to slow the progression of HSP and improve motor function.
- Anti-Inflammatory Properties: Our therapy helps reduce inflammation, protecting your neurons from further damage and alleviating pain and stiffness.
- Enhanced Mobility: Experience improved muscle strength and coordination, allowing you to regain independence and enjoy life to the fullest.
Patient Success Stories
Don’t just take our word for it—hear from our satisfied patients who have experienced remarkable improvements in their condition. Visit our Patient Testimonials page to read their inspiring journeys.
Take the First Step Towards a Better Future
Don’t let HSP dictate your life. Embrace the potential of stem cell therapy at Dream Body Clinic and take the first step towards a brighter, more mobile future. Our friendly and knowledgeable staff are here to answer any questions and guide you through the process.
Schedule Your Consultation Today
Ready to learn more? Contact us today to schedule your consultation and discover how Dream Body Clinic’s stem cell treatment for Hereditary Spastic Paraplegia can transform your life.
Call (307) 461-5393 For a Free Consultation
How do Mesenchymal Stem Cells Help with Hereditary Spastic Paraplegia?
Hereditary Spastic Paraplegia (HSP) is a group of inherited disorders characterized by progressive weakness and spasticity (stiffness) of the legs. The condition is caused by the degeneration of the upper motor neurons that control movement. There is currently no cure for HSP, but various treatments can help manage symptoms and improve quality of life.
Mesenchymal stem cells (MSCs) have shown to be a great therapeutic option for neurodegenerative diseases, including HSP, due to their ability to modulate immune responses, promote tissue repair, and potentially protect or regenerate damaged neurons. Since HSP is a genetic condition the MSCs can’t cure it, but they can improve symptoms and offer relief. Here is how MSCs can help with HSP:
Neuroprotection: MSCs can secrete various neurotrophic factors that support neuron survival and function, potentially slowing the progression of neurodegeneration in HSP.
Anti-inflammatory Effects: MSCs can modulate the immune system and reduce inflammation, which is often a component of neurodegenerative diseases. Reducing inflammation can help protect neurons from further damage.
Tissue Repair and Regeneration: MSCs can guide cells to differentiate into neural cells. MSCs can contribute to tissue repair and promote the regeneration of damaged neural tissues.
Improvement of Motor Function: By protecting neurons and reducing inflammation, MSCs can potentially improve motor function and reduce spasticity in individuals with HSP.
Releasing trophic factors: MSCs release various trophic factors, such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and glial-derived neurotrophic factor (GDNF), that promote nerve regeneration, survival, and growth.
Immune modulation: MSCs have immunomodulatory properties that can dampen the inflammatory response and promote tissue regeneration and repair.
Guide Cell Differentiation and Regeneration: MSCs have the ability to guide differentiation and regeneration of multiple cell types, including neurons, which can help improve nerve function and repair.
Extracellular matrix (ECM) remodeling: MSCs can also promote tissue remodeling by secreting ECM-degrading enzymes, which help promote the growth of new blood vessels and improve tissue repair.
Overall, the use of MSCs for the treatment of Hereditary Spastic Paraplegia have shown great results for patients.
What Neurotrophic Factors do MSCs Release to Help Nerve Regeneration?
Mesenchymal stem cells (MSCs) are known to release neurotrophic factors that promote cell growth, survival, and repair. Neurotrophic factors are a family of proteins that play an important role in the development and maintenance of the nervous system. MSCs release several neurotrophic factors, including:
Nerve growth factor (NGF): NGF is a protein that promotes the growth and survival of nerve cells. It plays a crucial role in the development, maintenance, and repair of the nervous system.
Brain-derived neurotrophic factor (BDNF): BDNF is involved in promoting the growth, differentiation, and survival of neurons in the brain and peripheral nervous system. It plays a key role in maintaining the synaptic plasticity that is vital for learning and memory.
Glial cell line-derived neurotrophic factor (GDNF): GDNF is a protein that protects and promotes the survival of neurons, including dopaminergic neurons. It also plays a crucial role in promoting the growth and development of nerve cells.
Insulin-like growth factor (IGF): IGF is a protein hormone that promotes cell growth, differentiation, and repair in various tissues, including the nervous system. It also has a role in neuroprotection and enhances the survival of nerve cells.
Vascular endothelial growth factor (VEGF): VEGF plays a crucial role in promoting the formation of new blood vessels, which is important for tissue repair and regeneration.
Ciliary neurotrophic factor (CNTF): CNTF is a protein that promotes the survival and growth of motor neurons in the peripheral nervous system. It has also been shown to promote the regeneration of damaged neurons, making it a promising candidate for the treatment of neurodegenerative diseases.
Fibroblast growth factor (FGF): FGF is a protein that plays a key role in cell growth, migration, and differentiation. In the nervous system, FGF stimulates the proliferation of neural stem cells and promotes the survival of neurons.
Platelet-derived growth factor (PDGF): PDGF is a protein that promotes cell proliferation and differentiation in various tissues, including the nervous system. It has been shown to support the survival and growth of neurons and Schwann cells in the peripheral nervous system.
Neurotrophin-3 (NT-3): NT-3 is a protein that promotes the growth and survival of various types of neurons, particularly sensory neurons. It has also been shown to promote the regeneration of damaged axons.
Transforming growth factor-beta (TGF-β): TGF-β is a protein that plays a key role in cell growth, differentiation, and repair. In the nervous system, TGF-β has been shown to promote the proliferation of neural stem cells and support the growth and survival of neurons.
Overall, the release of these neurotrophic factors by MSCs plays a crucial role in promoting the growth, survival, and repair of nerve cells. This mechanism underlies the therapeutic potential of MSC-based therapies for various neurological conditions.
How do the Mesenchymal Stem Cells Work With Nerve Growth Factor to Heal Hereditary Spastic Paraplegia Symptoms?
When mesenchymal stem cells (MSCs) can guide nerve growth factor (NGF) for the treatment of Hereditary Spastic Paraplegia, the two work together to promote nerve regeneration and repair.
NGF is a neurotrophic factor that plays a critical role in the growth, survival, and maintenance of various types of neurons. It can stimulate the growth of axons and promote the regeneration of damaged nerves.
NGF can work synergistically with the trophic factors released by the MSCs to enhance nerve regeneration and repair. MSCs can also help deliver NGF to the site of nerve damage, increasing its concentration and duration of action.
In addition, MSCs can also guide differentiation and regeneration of neurons and other cell types, which can help repopulate damaged or lost cells in the nerves. This process can further enhance the efficacy of NGF and promote the regeneration and repair of damaged nerves.
Nerve Growth Factor works amazingly well with mesenchymal stem cells for the regeneration of nerves.
How do Mesenchymal Stem Cells Work with Brain-Derived Neurotrophic Factor to Help Hereditary Spastic Paraplegia Symptoms?
Mesenchymal stem cells (MSCs) interact with brain-derived neurotrophic factor (BDNF) to promote various cellular processes, including cell proliferation, differentiation, and survival. BDNF is a neurotrophic factor that plays a vital role in the growth, survival, and maintenance of neurons in the central nervous system, including the brain.
When MSCs are combined with BDNF, the two interact in several ways:
Promoting neuronal differentiation: MSCs guide differentiation of neural cells, including neurons. BDNF can stimulate the differentiation of neurons, which can aid in neural repair and regeneration.
Enhancing synaptogenesis and neurite outgrowth: BDNF plays a vital role in the formation of synapses and the growth of neurites. MSCs, in combination with BDNF, can enhance synaptogenesis, neurite outgrowth, and neuronal connectivity.
Improving cognitive function: BDNF has been shown to improve cognitive function, particularly learning and memory, by promoting synaptic plasticity and neuronal survival. MSCs can help improve cognitive function by releasing BDNF and promoting the growth and repair of new neurons.
Overall, the MSCs working with BDNF offers a great treatment of various neurodegenerative diseases, including Hereditary Spastic Paraplegia, Traumatic Brain Injury, stroke and peripheral neuropathy.
Hereditary Spastic Paraplegia Stem Cell Treatment and Chemotaxis
Chemotaxis is the process by which cells are attracted or repelled by specific chemicals in their surrounding environment. The chemicals that act as the attractants or repellents are called chemotactic agents, or chemotaxis. Chemotaxis is an essential process for many biological functions, such as immune responses, wound healing, embryonic development, and bacterial movement.
In the context of regenerative medicine, MSCs are often used to repair or replace damaged tissues. Chemotaxis plays an essential role in the migration of MSCs to the site of tissue damage. When an injury occurs, cells in the damaged tissue release chemotactic agents that attract MSCs to the site of the injury. Once MSCs reach the damaged tissue, they can guide differentiation and regeneration of various cell types to help repair the damaged tissue.
Chemotaxis is regulated by several signaling pathways, including the phosphoinositide 3-kinase (PI3K)/Akt and mitogen-activated protein kinase (MAPK) pathways. These pathways help to regulate the migration and differentiation of MSCs by controlling the expression of various genes and proteins.
Chemotaxis is also an important process in immune responses, as immune cells must be able to migrate to sites of infection or injury to fight off pathogens and repair damaged tissues. In this context, chemotaxis is regulated by various cytokines and chemokines that are produced by the tissue.
Thus, chemotaxis is a fundamental biological process that plays a crucial role in tissue repair, immune responses, and many other physiological processes. This process is crucial for reversing Hereditary Spastic Paraplegia Symptoms.
How do Mesenchymal Stem Cells Regenerate Myelin Sheath?
Mesenchymal stem cells (MSCs) have the potential to regenerate myelin sheath by promoting a process known as remyelination. This process involves the repair and regeneration of damaged or destroyed myelin sheath, which is essential for the proper functioning of the nervous system.
MSCs can guide various types of cells, including oligodendrocytes, which are the cells responsible for producing myelin sheath. Once injected into the body, the mesenchymal stem cells migrate to the site of the damaged tissue and start generating new myelin-forming cells. MSCs can also produce growth factors and other signaling molecules that stimulate the growth and differentiation of endogenous oligodendrocytes, leading to remyelination in damaged areas.
In addition to direct remyelination, MSCs may play a supportive role in the regeneration process by modulating immune responses and reducing inflammation in the nervous system. By creating a conducive environment for remyelination, MSCs can enhance the healing process and improve the symptoms of Hereditary Spastic Paraplegia.
While the precise mechanisms of MSC-mediated remyelination in Hereditary Spastic Paraplegia are still under investigation, preclinical and clinical studies have shown promising results and results at Dream Body Clinic are confirming this.
How do Mesenchymal Stem Cells Regenerate Neural Tissues?
Mesenchymal stem cells (MSCs) can regenerate neural tissues by several mechanisms. MSCs are known to have a unique ability to guide multiple cell types, including neural cells such as neurons and glial cells, which make up the components of neural tissue. Thus, MSCs can directly generate new neural tissue by guiding these cell types and integrating into the existing neural networks.
Furthermore, MSCs can modulate the microenvironment of the nervous system in ways that can promote the formation of new neural tissues. For example, they can secrete growth factors and cytokines that stimulate endogenous stem cells to differentiate into neural cells. Additionally, MSCs can enhance the growth and survival of existing neural cells by decreasing inflammation, promoting blood vessel formation, and reducing oxidative stress.
Finally, MSCs can also exert their therapeutic effects by secreting extracellular vesicles (EVs). EVs are minute packets of material containing a variety of growth factors, cytokines, and microRNAs that exert neuroprotective and regenerative effects. Exosomes are the primary EV released by MSCs and they release far more than can be administered by clinics offering lyophilized exosomes from the lab. The other advantage is that MSCs know where to release these exosomes for best results whereas exosomes that are injected have no guidance. MSC-derived EVs can stimulate the formation of new neural tissue by promoting angiogenesis, increasing neuron survival, and reducing inflammatory responses.
Overall, the regenerative effects of MSCs on neural tissue come from a complex interplay between their ability to guide the development of new neural cells and their capability to modulate the microenvironment by producing growth factors, cytokines, and EVs (exosomes). As a result, MSCs hold significant potential for various neurological disorders that result from the damage of neural tissues.
How do Mesenchymal Stem Cells Protect the Nervous System?
Mesenchymal stem cells (MSCs) can protect the nervous system through several mechanisms. The nervous system is a complex network of neurons and supporting cells that perform a wide variety of critical functions, such as sensory perception, movement control, and cognitive processing. Many neurological disorders and injuries can damage the nervous system, leading to impaired functioning and various symptoms. MSCs can provide protection to the nervous system in the following ways:
Anti-inflammatory action: Inflammatory responses can cause damage to the nervous system, especially in chronic conditions such as Hereditary Spastic Paraplegia. MSCs have been shown to reduce inflammation by suppressing the activity of immune cells that contribute to inflammation and promoting the activity of anti-inflammatory immune cells. By decreasing inflammation, MSCs can help to protect the nervous system from damage.
Anti-apoptotic action: Apoptosis, or programmed cell death, can occur due to a wide variety of causes, such as chronic inflammation, oxidative stress, or injury. Apoptosis of nervous system cells can lead to widespread damage and symptoms. MSCs have been shown to reduce apoptosis by increasing the production of molecules that support cell survival.
Promotion of angiogenesis: Angiogenesis is the process by which new blood vessels are formed. Blood vessels are essential for supplying oxygen and nutrients to nervous system cells. MSCs can promote angiogenesis, which helps to maintain the health and functioning of nervous system cells.
Immunomodulatory activity: Along with their anti-inflammatory activity, MSCs can also modulate immune responses. This immunomodulatory activity can help to protect the nervous system by reducing the activity of immune cells that can cause damage and increasing the activity of cells that support healing and regeneration.
In summary, MSCs can protect the nervous system by decreasing inflammation, reducing apoptosis, promoting angiogenesis, and modulating immune responses. These properties make MSCs the best therapy for neurological conditions like Hereditary Spastic Paraplegia.
Hereditary Spastic Paraplegia Stem Cell Treatment Studies
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration
Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms
- Targeted stimulation of MSCs in peripheral nerve repair
- Mesenchymal stem cells to treat diabetic neuropathy: a long and strenuous way from bench to the clinic
- Bone marrow-derived mesenchymal stem/ stromal cells reverse the sensorial diabetic neuropathy via modulation of spinal neuroinflammatory cascades
- Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation
- MSC-Derived Exosomes-Based Therapy for Peripheral Nerve Injury: A Novel Therapeutic Strategy
- From tendon to nerve: an MSC for all seasons
Side Effects or Risks
The only side effects that have been documented are the following:
- 1 in 100 people will experience a slight fever and/or headache for a few hours after treatment or the next day. We have found that 500mg of Tylenol easily resolves this issue.
- Any treatment involving an injection such as an IV runs a risk of infection. We have never had a patient experience an infection due to our sterility protocols,.
- 1 in about 30 patients will experience some lower back pain near the intrathecal injection site. It typically lasts a few hours to a few days before fully dissipating. We provide tramacet to all patients as a way to deal with this if it occurs.
- 1 in about 30 patients will experience a migraine like headache and sometimes nausea with it from the intrathecal treatment. In most cases taking 1 tramacet will relieve these side effects. In some cases the headache can last a few hours to a few days. We provide tramacet to all patients just in case to deal with this.
- A very small percentage of patients for this treatment will be non-responders. As with any medication or treatment there is always a chance of no change. Tylenol does not always fix a headache as an example.
- We do not treat patients that have had cancer within the past 5 years. There is still no conclusive evidence linking stem cells to make cancer worse, but we prefer to stay on the side of safety until more information is available.
- As with any medical treatment there is no guarantee of results, but our outcomes have been great for the vast majority of patients.
- In all patients who receive an intravenous treatment of any sort, there is a risk of releasing a thrombus or plaque from the veins, even more so if the patient has mainly high cholesterol levels. If a thrombosis or phlebitis were to occur, it would occur immediately. This has not been an issue with our patients, but any sort of IV has this risk. This is why we do bloodwork for all patients to make sure that treatment is as safe as possible for them.
Our lab has over 8 years of experience cultivating mesenchymal stem cells with perfect safety and efficacy. See Stem Cell Certification by Clicking Here
How long do the Hereditary Spastic Paraplegia Stem Cell Treatment Results Last?
The results from the the Hereditary Spastic Paraplegia stem cell treatment can last for years or even indefinitely. This is because the stem cells are regenerating nerves and reprogramming your immune system to work the way it was designed to work. Once the nerves are regenerated then things will work the way they should with no pain. This will last because it is real regeneration and not just a pill to cover up symptoms.
The mesenchymal stem cells that are administered via IV will stay in the system for 8 months to a year. During that time they will interact with immune cells and seek out inflammation where they will guide cellular regeneration. After 8 to 12 months any MSCs that are free bound in your system will differentiate into an osteoblast (bone cell), adipocyte (fat cell) or chondrocyte (cartilage cell). They will then contain the donors HLA markers and your immune system will destroy and remove them. This is an easy process for your immune system and there is no negative reaction in your body from it. Some of the MSCs that were free bound from the IV will find capillaries to call home. They will attach and be considered a pericyte. When they do this they can live in your system indefinitely in a beneficial way to your system.
The Hereditary Spastic Paraplegia Stem Cell Treatment is allowing your body to heal like it did when you were a little kid. There are a lot of other benefits outside of just fixing your nerves and nervous system such as anti-aging. Click Here for An in depth look at how the stem cell IV works for Anti-Aging
How to get the Hereditary Spastic Paraplegia Stem Cell Treatment
In conclusion, the Hereditary Spastic Paraplegia stem cell treatment could be a promising solution for individuals who are facing this condition. The Dream Body Clinic provides personalized treatment plans using stem cells to repair and regenerate damage to the brain and spinal cord which may lead to improved mobility and relief of symptoms. While this treatment is not yet widely available, ongoing research suggests that it is a viable alternative to traditional Hereditary Spastic Paraplegia management methods. If you are interested in learning more about this treatment, we recommend calling us for a free consultation at (307) 461-5393. If you are ready to get the Hereditary Spastic Paraplegia Stem Cell Treatment then click the image below for details on how to book.