ABSTRACT for MESENCHYMAL STEM CELLS RESEARCH IN CARTILAGE REPAIR

MESENCHYMAL STEM CELLS RESEARCH IN CARTILAGE REPAIR – Advances in Mesenchymal Stem Cells (MSC) research has initiated thedevelopment of new therapeutic strategies that brings promise to patients sufferingfrom damaged cartilage. It has been generally accepted that research conducted indeveloped countries are more advanced than those of developing nations although,the need for the utilization of such technologies are more pronounced in the latter.Despite its importance, it is unclear as whether the research progress of developingcountries is comparable to that of developed nations. To determine this, Malaysia being a typical developing country was selected as a comparative model. A reviewon research related to MSC in cartilage repair or fundamental studies using MSCsfor the past 10 years (from 2001 till 2011) was performed using online researchdatabases which included PubMed, Scopus and ISI Web of Knowledge.RESULTS: Of the 42 countries, Malaysia ranked 22nd in number of publications,while amongst the Asia-Pacific countries Malaysia is number 6 of 9. Developedand developing countries contributed 80.1% and 19.9% of the published articles inthis field respectively. Despite being a developing country, China ranks second inthe world. There were significant differences (p<0.01) in the publication numbers,total budget for research and %GDP for research between the developed anddeveloping nations. The amount of GDP, %GDP for research and total budget forresearch demonstrate significant correlations (p<0.01). Although Malaysia rankslow in terms of total publication worldwide, it has the highest number of publications comparable to larger and more affluent countries such as Israel,Turkey and Norway. CONCLUSION: There appears to be a strong relationship between GDP and research publication in MSC for cartilage repair. Despite being adeveloping country with relatively lower GDP, Malaysia is progressingsignificantly in this area of research but remains remarkably behind China andother advanced countries

Dream Body Clinic is able to treat cartilage damaged joints such as; knees, shoulders, ankles, wrists, elbows, spine, hips, fingers and toes. We use mesenchymal stem cells derived from placenta and Wharton’s Jelly (Umbilical tissue). These mesenchymal stem cells are able to guide the cellular regeneration of cartilage for patients with arthritis.

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