COPD Stem Cell Treatment
Chronic Obstructive Pulmonary Disease – COPD stem cell treatment is a stem cell therapy done with an 200 million stem cell IV followed by 4 sessions of 25 million nebulized stem cells. COPD is one of those diseases that doctors currently can only manage the symptoms. Mesenchymal Stem Cells flip this paradigm as they have now been found to treat COPD with great success. When Mesenchymal Stem Cells (MSCs) are administered via IV they go directly to the lungs first. This is called the first pass and a great thing for COPD as the majority of the stem cells (approximately 80%) never get past the lungs and heart. The stem cells are attracted to inflammation and the lungs are full of it. They get to work by guiding the removal of fibrosis (scarring) and then guiding the cellular repair. We have seen the best success with COPD patients that had the route cause from damage via smoking or other issue. When the COPD is viral or bacterial we have a much lower success rate. In those cases we suggest the patient do 10 to 20 rounds of ozone therapy before coming for stem cell treatment. This is because the ozone can greatly weaken the virus or bacteria and when the stem cells are administered they super boost the immune system which can then eliminate the virus or bacterial infection.
To get started please fill out our intake form and then we will call for a free consultation – INTAKE FORM
Intranasal Stem Cell Application Study
Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of lung damage. This study shows that intranasal stem cell application helps heal the lungs and brain. We prefer to use a nebulized approach for intranasal application as more stem cells are able to get to the mucus membrane and pass to the blood stream to go straight to the brain.
- Blood Panel to give you a baseline to compare and measure effects
- 200 million mesenchymal stem cells administered at 100 million per day over the course of 2 days
- 25 million mesenchymal stem cells administered via nebulization twice a day for 2 days for a total of 100 million
- Lyophilized placenta injection
The first day you arrive is to settle in and rest. You fast that night and next morning until we do a blood panel around 8 or 9am. We also need to know what medications you are on as some medications need to be stopped for a few days leading up to this treatment. For the stem cells we need you to stop taking any Nonsteroidal anti-inflammatory drugs (NSAIDs) a week before getting stem cell treatment. You can use them afterwards. The most prominent NSAIDs are aspirin, ibuprofen and nap
Side Effects or Risks
The only side effects that have been documented are the following:
- 1 in 100 people will experience a slight fever for a few hours after treatment
Our lab has over 8 years specializing in Mesenchymal Stem Cell research. Our lab has done a maximum of 1 billion stem cells via IV with no negative side effects. See Stem Cell Certification by Clicking Here.
Studies into MSCs for COPD
- Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease
- Mesenchymal stromal cell therapy in COPD: from bench to bedside
- Preclinical Studies of (MSC) Administration in Chronic Obstructive Pulmonary Disease (COPD)
- A Placebo-Controlled, Randomized Trial of Mesenchymal Stem Cells in COPD
- Nebulized Stem Cells – Airway delivery of conditioned media from mesenchymal stem cells (MSC-CM) for COPD
- Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease
- Therapeutic potential of airway remodeling with MSCs
Why do we need Mesenchymal Stem Cells?
We need more stem cells as we age, but our body is using them up. When we are infants, we have the most stem cells that we will ever have and then by the time we grow up to bone maturity, we only have 10% of these cells left. Only 10% and that is all we have left to work with for the rest of our lives. Cells die off as we age and that percentage goes down even further every year.
So How do Mesenchymal Stem Cells Work?
Mesenchymal Stem cell therapies work by stimulating the body to regenerate itself. Their magic is not in their ability to become or replace different tissues or cells, but in their production of trophic factors, bioactive molecules produced in response to the environment in which the cells are in. These secreted chemicals aid in repairing tissue and the recruitment of new blood vessels to support nutrient flow to the area and decrease inflammation. By repairing tissue, recruiting new blood vessels and increased nutrient flow your body will start to behave the way it is meant to operate. So it is not the cells themselves that work the magic. It is what the cells secrete that has such medicinal potential.
Only available at our Puerto Vallarta Stem Cells clinic. Puerto Vallarta stem cell treatment.
More info on the Mesenchymal Stem Cell Secretions
Mesenchymal Stem cells (MSCs) secrete a wide range of cellular products, molecules, exosomes (part of the genome thats inside RNA. Progams protein coding) and microvesicles ( Microvesicles play a role in intercellular communication and can transport mRNA, miRNA, and proteins between cells.) That act in different ways to stimulate the body’s healing process.
Growth Factors Aid in Healing
Growth factors (A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Usually it is a protein or a steroid hormone. Growth factors are important for regulating a variety of cellular processes. Cytokines (Cytokines are a broad and loose category of small proteins that are important in cell signaling. Their release has an effect on the behavior of cells around them. It can be said that cytokines are involved in autocrine signaling, paracrine signalingand endocrine signaling as immunomodulating agents.) , hormones, and cellular mitochondria and RNA are among the secreted bioactive molecules and cellular material that characterize the wide range of activities carried out by mesenchymal stem cells. When considering that the main function of stem cells lies in their secretome. This is the bioactive molecules they secrete. This means they don’t have the ability to differentiate into new tissue, but intead allow your own body to heal itself properly. Isolating these trophic factors separate from the cells offers an intriguing mode of treatment.
Puerto Vallarta stem cell treatment.
Do the Mesenchymal Stem Cell Treatment Results Last?
The results from 200 million stem cell IV + 4 nebulized sessions are lasting because your body is able to heal itself like when you were younger. That healing does not go away fast, just think of how many years it took to get you where you are. By getting this treatment once or twice a year, your body will be able to regenerate more and more. The 300 million cells will stay in your system until they mature after a year. Many will find capillaries to call home and those can stay with you indefinitely. So any extra capillary space available is filled with the stem cells and they stay with you. The rest of the stem cells circulate in your blood stream looking for areas of inflammation and cells to help. Mesenchymal stem cells are the only cells that have been found able to donate mitochondria to weak or injured cells, thus making them whole again. The stem cells that don’t find a home in your capillaries stay for up to 8 months at which time they mature and your body flushes them out.
Lyophilized Placenta Injection Subcutaneous Injection
The placenta is loaded with nutrients, vitamins and hormones. This is why almost all animals eat the placenta after birth. Fortunately we have found a much more effective way to get all this good stuff into your system. We are able to reconstitute the lyophilized placenta with saline solution and then inject it subcutaneously. The solution absorbs into the fat and is slowly released over the next 3 months. This keeps your vitamin, mineral and nutrient profile optimized for 3 months post treatment. I like to think of the mesenchymal stem cells as the managers on the construction site. They are guiding the building by sending out cytokine, chemokines and trophic factors to the cells which in this case are like the workers. The placenta injection is like ensuring that the workers have all of the bricks and material to build with. These hormones, nutrients, vitamins and minerals will help the live stem cells from the IV to live longer and do more repair.
COPD Stem Cell Study
Allogeneic umbilical cord-derived mesenchymal stem cell transplantation for treating chronic obstructive pulmonary disease: a pilot clinical study.
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. COPD results from chronic inflammation of the lungs. Current treatments, including physical and chemical therapies, provide limited results. Stem cells, particularly mesenchymal stem cells (MSCs), are used to treat COPD. Here, we evaluated the safety and efficacy of umbilical cord-derived (UC)-MSCs for treating COPD.
Twenty patients were enrolled, 9 at stage C and 11 at stage D per the Global Initiative for Obstructive Lung Disease (GOLD) classification. Patients were infused with 106 cells/kg of expanded allogeneic UC-MSCs. All patients were followed for 6 months after the first infusion. The treatment end-point included a comprehensive safety evaluation, pulmonary function testing (PFT), and quality-of-life indicators including questionnaires, the 6-min walk test (6MWT), and systemic inflammation assessments. All patients completed the full infusion and 6-month follow-up.
No infusion-related toxicities, deaths, or severe adverse events occurred that were deemed related to UC-MSC administration. The UC-MSC-transplanted patients showed a significantly reduced Modified Medical Research Council score, COPD assessment test, and number of exacerbations. However, the forced expiratory volume in 1 s, C-reactive protein, and 6MWT values were nonsignificantly reduced after treatment (1, 3, and 6 months) compared with those before the treatment.
Systemic UC-MSC administration appears to be safe in patients with moderate-to-severe COPD, can significantly improve their quality of life, and provides a basis for subsequent cell therapy investigations.
COPD Stem Cell Treatment Payment Options
For all stem cell procedures we accept Visa, Mastercard, American Express, Cash or Crypto Currency at our clinic at the San Javier Hospital in Puerto Vallarta, Mexico.
To get started please fill out our intake form and then we will call for a free consultation – INTAKE FORM